unfolded

v.

develop or come to a promising stage

同义词：blossomblossom outblossom forth

open to the view

"A walk through town will unfold many interesting buildings"

extend or stretch out to a greater or the full length

同义词：stretchstretch outextend

spread out or open from a closed or folded state

同义词：spreadspread outopen

ER stress and the unfolded protein response.
Natively unfolded proteins: a point where biology waits for physics.
Orchestrating the unfolded protein response in health and disease.
Tripartite management of unfolded proteins in the endoplasmic reticulum
Why are "natively unfolded"proteins unstructured under physiologic conditions?
Translational control is required for the unfolded protein response and in vivo glucose homeostasis.
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response.
Perk is essential for translational regulation and cell survival during the unfolded protein response
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol. 2007;8(7):519-529